{"id":2747,"date":"2025-10-22T21:43:10","date_gmt":"2025-10-22T13:43:10","guid":{"rendered":"https:\/\/www.nobelstars.cn\/?p=2747"},"modified":"2025-10-22T21:43:10","modified_gmt":"2025-10-22T13:43:10","slug":"2025%e8%af%ba%e8%b4%9d%e5%b0%94%e7%94%9f%e7%90%86%e5%ad%a6%e6%88%96%e5%8c%bb%e5%ad%a6%e5%a5%96%e6%8f%ad%e6%99%93%ef%bc%9a%e5%85%8d%e7%96%ab%e7%b3%bb%e7%bb%9f%e7%9a%84%e7%bb%b4%e7%a8%b3","status":"publish","type":"post","link":"https:\/\/www.nobelstars.cn\/?p=2747","title":{"rendered":"2025\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u63ed\u6653\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u201c\u7ef4\u7a33\u5bc6\u7801\u201d"},"content":{"rendered":"
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\u5bfc\u8bed<\/strong><\/section>\n<\/section>\n<\/section>\n<\/section>\n
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\u592e\u89c6\u65b0\u95fb\u6d88\u606f\uff0c\u5f53\u5730\u65f6\u95f410\u67086\u65e5\uff0c\u745e\u5178\u5361\u7f57\u7433\u533b\u5b66\u9662\u5ba3\u5e03\uff0c\u5c062025\u5e74\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u6388\u4e88\u79d1\u5b66\u5bb6\u739b\u4e3d\u00b7E\u00b7\u5e03\u4f26\u79d1\uff08Mary E. Brunkow\uff09\u3001\u5f17\u96f7\u5fb7\u00b7\u62c9\u59c6\u65af\u5fb7\u5c14\uff08Fred Ramsdell\uff09\u548c\u5742\u53e3\u5fd7\u6587\uff08Shimon Sakaguchi\uff09\uff0c\u8868\u5f70\u4ed6\u4eec\u5728\u5916\u5468\u514d\u75ab\u8010\u53d7\u65b9\u9762\u7684\u7814\u7a76\u8d21\u732e\u3002<\/section>\n<\/section>\n<\/section>\n
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\u4e00\u3001\u4e00\u9879\u8fdf\u523030\u5e74\u7684\u8bfa\u5956\u53d1\u73b0<\/em><\/strong><\/section>\n<\/section>\n
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\u65e9\u5728\u4e0a\u4e16\u7eaa 70 \u5e74\u4ee3\uff0c\u514d\u75ab\u5b66\u754c\u4fbf\u7387\u5148\u63d0\u51fa\u300c\u6291\u5236\u6027 T \u7ec6\u80de\uff08Suppressor T cells\uff09\u300d\u7684\u6982\u5ff5\u3002\u4f46\u53d7\u9650\u4e8e\u5f53\u65f6\u5b9e\u9a8c\u6280\u672f\u7684\u843d\u540e\uff0c\u4e0d\u540c\u56e2\u961f\u7684\u7814\u7a76\u7ed3\u679c\u59cb\u7ec8\u65e0\u6cd5\u7edf\u4e00\uff0c\u751a\u81f3\u76f8\u4e92\u77db\u76fe \u2014\u2014 \u5230\u4e86\u4e0a\u4e16\u7eaa 80 \u5e74\u4ee3\u521d\uff0c\u8fd9\u4e00\u66fe\u7ecf\u88ab\u5bc4\u4e88\u539a\u671b\u7684\u6982\u5ff5\uff0c\u5df2\u8fd1\u4e4e\u88ab\u6574\u4e2a\u9886\u57df\u5f7b\u5e95\u5e9f\u5f03\u3002<\/p>\n<\/section>\n

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\u8f6c\u6298\u53d1\u751f\u5728 1995 \u5e74\uff1a\u5742\u53e3\u5fd7\u6587\u53d1\u8868\u5173\u952e\u6027\u7814\u7a76\uff0c\u91cd\u65b0\u63ed\u793a\u4e86 CD4\u207aCD25\u207a T \u7ec6\u80de\u7684\u514d\u75ab\u6291\u5236\u529f\u80fd\uff1b2000 \u5e74\uff0c\u4ed6\u8fdb\u4e00\u6b65\u5c06\u8fd9\u7c7b\u7ec6\u80de\u6b63\u5f0f\u547d\u540d\u4e3a\u300c\u8c03\u8282\u6027 T \u7ec6\u80de\uff08Treg\uff09\u300d\uff0c\u8fd9\u4e00\u6c89\u5bc2\u8fd1 20 \u5e74\u7684\u514d\u75ab\u6982\u5ff5<\/span>\uff0c\u624d\u7ec8\u4e8e\u5f97\u4ee5\u300c\u590d\u6d3b\u300d\u3002<\/p>\n<\/section>\n
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\u8fdb\u5165 2001 \u81f3 2003 \u5e74\uff0cBrunkow \u4e0e Ramsdell \u7684\u7814\u7a76\u76f8\u7ee7\u8ddf\u8fdb\uff0c\u9996\u6b21\u5728\u5206\u5b50\u5c42\u9762\u6e05\u6670\u8bc1\u5b9e\u4e86 Treg \u7684\u5ba2\u89c2\u5b58\u5728\u4e0e\u5177\u4f53\u4f5c\u7528\u673a\u5236\u3002\u81f3\u6b64\uff0cTreg \u4e0d\u518d\u662f\u4e00\u4e2a\u6a21\u7cca\u7684\u300c\u73b0\u8c61\u89c2\u5bdf\u300d\uff0c\u800c\u662f\u8f6c\u53d8\u4e3a\u6709\u660e\u786e\u5206\u5b50\u4f9d\u636e\u7684\u300c\u673a\u5236\u9610\u91ca\u300d\uff0c\u7814\u7a76\u57fa\u7840\u88ab\u5f7b\u5e95\u592f\u5b9e\u3002<\/p>\n<\/section>\n

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Brunkow \u4e0e Ramsdell \u53d1\u73b0\u4e86 scurfy \u7a81\u53d8<\/p>\n

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They discovered how the immune system is kept in check.<\/strong><\/p>\n
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The body\u2019s powerful immune system must be regulated, or it may attack our own organs. Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi are awarded the Nobel Prize in Physiology or Medicine 2025 for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body.<\/p>\n

Every day, our immune system protects us from thousands of different microbes trying to invade our bodies. These all have different appearances, and many have developed similarities with human cells as a form of camouflage. So how does the immune system determine what it should attack and what it should defend?<\/p>\n

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi are awarded the Nobel Prize in Physiology or Medicine 2025 for their fundamental discoveries relating to peripheral immune tolerance. The laureates identified the immune system\u2019s security guards, regulatory T cells, which prevent immune cells from attacking our own body.<\/p>\n

\u201cTheir discoveries have been decisive for our understanding of how the immune system functions and why we do not all develop serious autoimmune diseases,\u201d says Olle K\u00e4mpe, chair of the Nobel Committee.<\/p>\n

Shimon Sakaguchi was swimming against the tide in 1995, when he made the first key discovery. At the time, many researchers were convinced that immune tolerance only developed due to potentially harmful immune cells being eliminated in the thymus, through a process called central tolerance. Sakaguchi showed that the immune system is more complex and discovered a previously unknown class of immune cells, which protect the body from autoimmune diseases.<\/p>\n

Mary Brunkow and Fred Ramsdell made the other key discovery in 2001, when they presented the explanation for why a specific mouse strain was particularly vulnerable to autoimmune diseases. They had discovered that the mice have a mutation in a gene that they named Foxp3. They also showed that mutations in the human equivalent of this gene cause a serious autoimmune disease, IPEX.<\/p>\n

Two years after this, Shimon Sakaguchi was able to link these discoveries. He proved that the Foxp3 gene governs the development of the cells he identified in 1995. These cells, now known as regulatory T cells, monitor other immune cells and ensure that our immune system tolerates our own tissues.<\/p>\n

The laureates\u2019 discoveries launched the field of peripheral tolerance, spurring the development of medical treatments for cancer and autoimmune diseases. This may also lead to more successful transplantations. Several of these treatments are now undergoing clinical trials.<\/p>\n<\/section>\n

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2025\u5e74\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u63ed\u6653<\/p>\n<\/section>\n

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\u201c\u5173\u4e8e\u5916\u5468\u514d\u75ab\u8010\u53d7\u7684\u53d1\u73b0\u201d<\/strong><\/section>\n<\/section>\n<\/section>\n
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\u8bfa\u8d1d\u5c14\u59d4\u5458\u4f1a\u4e3b\u5e2d\u5965\u52d2\u30fb\u574e\u4f69\uff08Olle K\u00e4mpe\uff09\u8868\u793a\uff1a\u201c\u4ed6\u4eec\u7684\u53d1\u73b0\u5bf9\u6211\u4eec\u7406\u89e3\u514d\u75ab\u7cfb\u7edf\u7684\u8fd0\u4f5c\u673a\u5236\uff0c\u4ee5\u53ca\u4e3a\u4f55\u5e76\u975e\u6240\u6709\u4eba\u90fd\u4f1a\u60a3\u4e0a\u4e25\u91cd\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u8d77\u5230\u4e86\u51b3\u5b9a\u6027\u4f5c\u7528\u3002\u201d<\/p>\n

1995 \u5e74\uff0c\u4e0b\u7530\u7ae0\u505a\u51fa\u4e86\u9996\u4e2a\u5173\u952e\u53d1\u73b0\uff0c\u5f53\u65f6\u4ed6\u7684\u89c2\u70b9\u4e0e\u4e3b\u6d41\u8ba4\u77e5\u76f8\u6096\u3002\u5728\u90a3\u4e2a\u5e74\u4ee3\uff0c\u8bb8\u591a\u7814\u7a76\u8005\u575a\u4fe1\uff0c\u514d\u75ab\u8010\u53d7\u7684\u5f62\u6210\u4ec5\u4ec5\u662f\u56e0\u4e3a\u5177\u6709\u6f5c\u5728\u5371\u5bb3\u6027\u7684\u514d\u75ab\u7ec6\u80de\u5728\u80f8\u817a\u4e2d\u901a\u8fc7\u4e00\u79cd\u540d\u4e3a \u201c\u4e2d\u67a2\u8010\u53d7\u201d \u7684\u8fc7\u7a0b\u88ab\u6e05\u9664\u3002\u800c\u4e0b\u7530\u7ae0\u5219\u8bc1\u660e\uff0c\u514d\u75ab\u7cfb\u7edf\u7684\u673a\u5236\u66f4\u4e3a\u590d\u6742\uff0c\u4ed6\u8fd8\u53d1\u73b0\u4e86\u4e00\u7c7b\u6b64\u524d\u672a\u77e5\u7684\u514d\u75ab\u7ec6\u80de \u2014\u2014 \u8fd9\u7c7b\u7ec6\u80de\u80fd\u4fdd\u62a4\u4eba\u4f53\u514d\u53d7\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u4fb5\u5bb3\u3002<\/p>\n

2001 \u5e74\uff0c\u739b\u4e3d\u30fb\u5e03\u4f26\u79d1\u548c\u5f17\u96f7\u5fb7\u30fb\u62c9\u59c6\u65af\u5fb7\u5c14\u53d6\u5f97\u4e86\u53e6\u4e00\u9879\u5173\u952e\u7a81\u7834\uff1a\u4ed6\u4eec\u63ed\u793a\u4e86\u67d0\u4e00\u7279\u5b9a\u54c1\u7cfb\u5c0f\u9f20\u4e3a\u4f55\u6781\u6613\u60a3\u4e0a\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002\u7814\u7a76\u53d1\u73b0\uff0c\u8fd9\u7c7b\u5c0f\u9f20\u4f53\u5185\u5b58\u5728\u4e00\u4e2a\u57fa\u56e0\u7a81\u53d8\uff0c\u4ed6\u4eec\u5c06\u8be5\u57fa\u56e0\u547d\u540d\u4e3aFoxp3\u3002\u6b64\u5916\uff0c\u4e24\u4eba\u8fd8\u8bc1\u5b9e\uff0c\u4eba\u7c7b\u4f53\u5185\u4e0e\u8be5\u57fa\u56e0\u5bf9\u5e94\u7684\u57fa\u56e0\u82e5\u53d1\u751f\u7a81\u53d8\uff0c\u4f1a\u5f15\u53d1\u4e00\u79cd\u4e25\u91cd\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5 \u2014\u2014IPEX \u7efc\u5408\u5f81\uff08\u514d\u75ab\u5931\u8c03\u3001\u591a\u5185\u5206\u6ccc\u817a\u75c5\u3001\u80a0\u75c5\u3001X \u8fde\u9501\u7efc\u5408\u5f81\uff09\u3002<\/p>\n

\u4e24\u5e74\u540e\uff0c\u4e0b\u7530\u7ae0\u6210\u529f\u5c06\u8fd9\u4e9b\u53d1\u73b0\u5173\u8054\u8d77\u6765\u3002\u4ed6\u8bc1\u5b9e\uff0cFoxp3\u57fa\u56e0<\/span>\u8c03\u63a7\u7740\u4ed6\u5728 1995 \u5e74\u53d1\u73b0\u7684\u90a3\u7c7b\u7ec6\u80de\u7684\u53d1\u80b2\u3002\u5982\u4eca\uff0c\u8fd9\u7c7b\u7ec6\u80de\u88ab\u79f0\u4e3a \u201c\u8c03\u8282\u6027 T \u7ec6\u80de\u201d\uff0c\u5b83\u4eec\u4f1a\u76d1\u63a7\u5176\u4ed6\u514d\u75ab\u7ec6\u80de\uff0c\u786e\u4fdd\u514d\u75ab\u7cfb\u7edf\u5bf9\u4eba\u4f53\u81ea\u8eab\u7ec4\u7ec7\u4fdd\u6301 \u201c\u8010\u53d7\u201d\u3002<\/p>\n

\u4e09\u4f4d\u83b7\u5956\u8005\u7684\u53d1\u73b0\u5f00\u521b\u4e86 \u201c\u5916\u5468\u8010\u53d7\u201d \u8fd9\u4e00\u7814\u7a76\u9886\u57df\uff0c\u63a8\u52a8\u4e86\u764c\u75c7\u548c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u76f8\u5173\u7597\u6cd5\u7684\u7814\u53d1\uff0c\u4e5f\u6709\u671b\u63d0\u9ad8\u5668\u5b98\u79fb\u690d\u7684\u6210\u529f\u7387\u3002\u76ee\u524d\uff0c\u5df2\u6709\u591a\u9879\u57fa\u4e8e\u8fd9\u4e9b\u53d1\u73b0\u7684\u7597\u6cd5\u8fdb\u5165\u4e86\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002<\/p>\n<\/section>\n

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\u4e09\u3001\u83b7\u5956\u4eba\u8be6\u7ec6\u4fe1\u606f<\/em><\/strong><\/p>\n<\/section>\n<\/section>\n
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Mary E. Brunkow\uff0c1961\u5e74\u51fa\u751f\u3002\u7f8e\u56fd\u666e\u6797\u65af\u987f\u5927\u5b66\u535a\u58eb\u3002\u7f8e\u56fd\u897f\u96c5\u56fe\u7cfb\u7edf\u751f\u7269\u5b66\u7814\u7a76\u6240\u9ad8\u7ea7\u9879\u76ee\u7ecf\u7406\u3002<\/section>\n
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Fred Ramsdell\uff0c1960\u5e74\u51fa\u751f\u30021987\u5e74\u83b7\u5f97\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u6d1b\u6749\u77f6\u5206\u6821\u535a\u58eb\u5b66\u4f4d\u3002\u73b0\u4efb\u7f8e\u56fd\u65e7\u91d1\u5c71\u7d22\u8bfa\u739b\u751f\u7269\u6cbb\u7597\u516c\u53f8\u79d1\u5b66\u987e\u95ee\u3002<\/section>\n
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Shimon Sakaguchi\uff0c1951\u5e74\u751f\u30021976\u5e74\u83b7\u5f97\u65e5\u672c\u4eac\u90fd\u5927\u5b66\u533b\u5b66\u535a\u58eb\u5b66\u4f4d\uff0c1983\u5e74\u83b7\u5f97\u535a\u58eb\u5b66\u4f4d\u3002\u65e5\u672c\u5927\u962a\u5927\u5b66\u514d\u75ab\u5b66\u524d\u6cbf\u7814\u7a76\u4e2d\u5fc3\u6770\u51fa\u6559\u6388\u3002<\/section>\n
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\u56db\u3001\u8fc7\u53bb10\u5e74<\/em><\/strong>\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u5f97\u4e3b\u540d\u5355<\/em><\/strong><\/section>\n<\/section>\n<\/section>\n<\/section>\n
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2024\u5e74<\/strong>–\u7f8e\u56fd\u79d1\u5b66\u5bb6Victor Ambros\u548cGary Ruvkun\u83b7\u5956\uff0c\u4ee5\u8868\u5f70\u4ed6\u4eec\u201c\u53d1\u73b0microRNA\u53ca\u5176\u5728\u8f6c\u5f55\u540e\u57fa\u56e0\u8c03\u63a7\u4e2d\u7684\u4f5c\u7528\u201d\u3002<\/p>\n

2023\u5e74<\/strong>\u2014\u2014\u7f8e\u56fd\u79d1\u5b66\u5bb6Katalin Karik\u00f3\u548cDrew Weissman\u83b7\u5956\uff0c\u83b7\u5956\u7406\u7531\u662f\u201c\u53d1\u73b0\u6838\u82f7\u57fa\u4fee\u9970\uff0c\u5f00\u53d1\u51fa\u4e86\u6709\u6548\u7684\u5bf9\u6297COVID-19\u7684mRNA\u75ab\u82d7\u201d\u3002<\/p>\n

2022\u5e74<\/strong>\u2014\u2014\u745e\u5178\u79d1\u5b66\u5bb6Svante P\u00e4\u00e4bo\u83b7\u5956\uff0c\u83b7\u5956\u7406\u7531\u662f\u201c\u5728\u5df2\u706d\u7edd\u53e4\u4eba\u7c7b\u57fa\u56e0\u7ec4\u548c\u4eba\u7c7b\u8fdb\u5316\u65b9\u9762\u7684\u53d1\u73b0\u201d\u3002<\/p>\n

2021\u5e74<\/strong>\u2014\u2014\u7f8e\u56fd\u79d1\u5b66\u5bb6David Julius\u3001Ardem Patapoutian\u83b7\u5956\uff0c\u83b7\u5956\u7406\u7531\u662f\u201c\u53d1\u73b0\u6e29\u5ea6\u548c\u89e6\u89c9\u7684\u53d7\u4f53\u201d\u3002<\/p>\n

2020\u5e74<\/strong>\u2014\u2014\u7f8e\u82f1\u4e09\u4f4d\u79d1\u5b66\u5bb6Harvey J. Alter\u3001Michael Houghton\u548cCharles M. Rice\u83b7\u5956\uff0c\u83b7\u5956\u7406\u7531\u662f\u201c\u53d1\u73b0\u4e19\u578b\u809d\u708e\u75c5\u6bd2\u201d\u3002<\/p>\n

2019\u5e74<\/strong>\u2014\u2014\u7f8e\u82f1\u4e09\u4f4d\u79d1\u5b66\u5bb6William G. Kaelin Jr\u3001Sir Peter J. Ratcliffe\u548cGregg L. Semenza\u83b7\u5956\uff0c\u83b7\u5956\u7406\u7531\u662f\u201c\u53d1\u73b0\u4e86\u7ec6\u80de\u5982\u4f55\u611f\u77e5\u548c\u9002\u5e94\u6c27\u6c14\u7684\u53ef\u7528\u6027\u201d\u3002<\/p>\n

2018\u5e74<\/strong>\u2014\u2014\u7f8e\u56fd\u79d1\u5b66\u5bb6James P. Allision\u548c\u65e5\u672c\u79d1\u5b66\u5bb6Tasuku Honjo\u83b7\u5956\uff0c\u83b7\u5956\u7406\u7531\u662f\u201c\u53d1\u73b0\u4e86\u6291\u5236\u8d1f\u9762\u514d\u75ab\u8c03\u8282\u7684\u764c\u75c7\u7597\u6cd5\u201d\u3002<\/p>\n

2017\u5e74<\/strong>\u2014\u2014\u4e09\u4f4d\u7f8e\u56fd\u79d1\u5b66\u5bb6Jeffrey C. Hall\u3001Michael Rosbash\u548cMichael W. Young\u83b7\u5956\uff0c\u83b7\u5956\u7406\u7531\u662f\u201c\u53d1\u73b0\u4e86\u8c03\u63a7\u663c\u591c\u8282\u5f8b\u7684\u5206\u5b50\u673a\u5236\u201d\u3002<\/p>\n

2016\u5e74<\/strong>\u2014\u2014\u65e5\u672c\u79d1\u5b66\u5bb6Yoshinori Ohsumi\u83b7\u5956\uff0c\u83b7\u5956\u7406\u7531\u662f\u201c\u53d1\u73b0\u4e86\u7ec6\u80de\u81ea\u566c\u673a\u5236\u201d\u3002<\/p>\n

2015\u5e74<\/strong>\u2014\u2014\u4e2d\u56fd\u79d1\u5b66\u5bb6\u5c60\u5466\u5466\u83b7\u5956\uff0c\u83b7\u5956\u7406\u7531\u662f\u201c\u6709\u5173\u759f\u75be\u65b0\u7597\u6cd5\u7684\u53d1\u73b0\u201d\uff1b\u53e6\u5916\u4e24\u4f4d\u83b7\u5956\u79d1\u5b66\u5bb6\u4e3a\u7231\u5c14\u5170\u7684William C. Campbell\u548c\u65e5\u672c\u7684Satoshi \u014dmura\uff0c\u83b7\u5956\u7406\u7531\u662f\u201c\u6709\u5173\u86d4\u866b\u5bc4\u751f\u866b\u611f\u67d3\u65b0\u7597\u6cd5\u7684\u53d1\u73b0\u201d\u3002<\/p>\n<\/section>\n

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\u4e94\u3001\u5173\u4e8e\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956<\/em><\/strong><\/p>\n<\/section>\n<\/section>\n
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\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u662f\u5168\u7403\u79d1\u5b66\u754c\u6700\u5d07\u9ad8\u7684\u5956\u9879\u4e4b\u4e00\uff0c\u7531\u745e\u5178\u79d1\u5b66\u5bb6\u3001\u4f01\u4e1a\u5bb6\u963f\u5c14\u5f17\u96f7\u5fb7\u00b7\u8bfa\u8d1d\u5c14\uff08Alfred Nobel\uff09\u57281895\u5e74\u901a\u8fc7\u9057\u5631\u8bbe\u7acb\uff0c\u65e8\u5728\u8868\u5f70\u90a3\u4e9b\u5728\u751f\u7406\u5b66\u6216\u533b\u5b66\u9886\u57df\u4e3a\u4eba\u7c7b\u5065\u5eb7\u548c\u751f\u547d\u79d1\u5b66\u505a\u51fa\u6770\u51fa\u8d21\u732e\u7684\u79d1\u5b66\u5bb6\u4eec\u3002\u81ea1901\u5e74\u9996\u6b21\u9881\u5956\u4ee5\u6765\uff0c\u8be5\u5956\u89c1\u8bc1\u4e86\u65e0\u6570\u751f\u547d\u79d1\u5b66\u548c\u533b\u5b66\u7684\u7a81\u7834\u6027\u6210\u679c\uff0c\u5e76\u6210\u4e3a\u5168\u7403\u77a9\u76ee\u7684\u79d1\u5b66\u76db\u4e8b\u3002\u6839\u636e\u8bfa\u8d1d\u5c14\u7684\u9057\u5631\uff0c\u8bfa\u8d1d\u5c14\u5956\u6700\u521d\u7684\u4e94\u4e2a\u5956\u9879\uff08\u5316\u5b66\u5956\uff0c\u7269\u7406\u5956\uff0c\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\uff0c\u6587\u5b66\u5956\u4ee5\u53ca\u548c\u5e73\u5956\uff0c\u7ecf\u6d4e\u5b66\u5956\u57281968\u5e74\u52a0\u5165\uff09\u7531\u4e0d\u540c\u7684\u673a\u6784\u8d1f\u8d23\u8bc4\u9009\u548c\u9881\u53d1\u3002\u5728\u591a\u5e74\u7ec4\u7ec7\u534f\u8c03\u4e0b\u5f62\u6210\u7684\u9881\u5956\u987a\u5e8f\u4f20\u7edf\u4e2d\uff0c\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u4e8e\u5341\u6708\u7684\u7b2c\u4e00\u4e2a\u661f\u671f\u3001\u5728\u6240\u6709\u5956\u9879\u4e2d\u7b2c\u4e00\u4e2a\u63ed\u6653\uff0c\u62c9\u5f00\u201c\u8bfa\u5956\u6708\u201d\u7684\u5e37\u5e55\u3002<\/section>\n
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\u00a0\u4ece1901\u5e74\u52302024\u5e74\uff0c\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u5171\u9881\u53d1\u4e86115\u6b21\u3002\u6ca1\u6709\u9881\u53d1\u76849\u5e74\u5206\u522b\u662f1915\u30011916\u30011917\u30011918\u30011921\u30011925\u30011940\u30011941\u30011942\u5e74\u3002\u4ece1901\u5e74\u81f32024\u5e74\uff0c\u5171229\u4eba\u83b7\u5956\u3002113\u6b21\u9881\u5956\u4e2d\uff0c40\u6b21\u4e3a\u5355\u72ec\u83b7\u5956\u8005\uff0c36\u6b21\u4e3a2\u4eba\u5171\u4eab\uff0c39\u6b21\u4e3a3\u4eba\u5171\u4eab\u3002<\/p>\n

\u8fd1\u5341\u5e74\u6765\uff0c\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u5448\u73b0\u591a\u6837\u5316\u8d8b\u52bf\uff0c\u6db5\u76d6\u5404\u4e2a\u5b50\u5b66\u79d1\uff0c\u5305\u62ec\u7ec6\u80de\u751f\u7269\u5b66\u3001\u514d\u75ab\u5b66\u3001\u9057\u4f20\u5b66\u7b49\u3002\u5176\u4e2d\uff0c\u57fa\u7840\u7814\u7a76\u5360\u591a\u6570\uff0c\u4e5f\u6709\u91cd\u5927\u4e34\u5e8a\u6210\u679c\u83b7\u5956\u3002\u5728\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u7684\u53d1\u5c55\u5386\u53f2\u4e2d\uff0c\u8bf8\u591a\u7814\u7a76\u6df1\u523b\u5f71\u54cd\u4e86\u4e34\u5e8a\u533b\u5b66\u7684\u5b9e\u8df5\uff0c\u4e3a\u4eba\u7c7b\u653b\u514b\u75be\u75c5\u5f00\u8f9f\u4e86\u5168\u65b0\u7684\u9053\u8def\u3002<\/p>\n<\/section>\n

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\u6700\u5e74\u8f7b\u548c\u6700\u5e74\u957f\u7684\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u5f97\u4e3b<\/strong><\/p>\n

\u6700\u5e74\u8f7b\u7684\u83b7\u5956\u8005\u662f\u52a0\u62ff\u5927\u79d1\u5b66\u5bb6\u5f17\u96f7\u5fb7\u91cc\u514b\u00b7\u73ed\u5ef7\uff08Frederick G. Banting\uff09\uff0c1923\u5e74\u56e0\u201c\u53d1\u73b0\u80f0\u5c9b\u7d20\u201d\u83b7\u5956\uff0c\u65f6\u5e7432\u5c81\u3002<\/p>\n

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