{"id":2946,"date":"2025-10-24T23:45:46","date_gmt":"2025-10-24T15:45:46","guid":{"rendered":"https:\/\/www.nobelstars.cn\/?p=2946"},"modified":"2025-10-24T23:45:53","modified_gmt":"2025-10-24T15:45:53","slug":"%e8%af%ba%e5%a5%96%e7%ba%a7%e5%8f%91%e7%8e%b0%e8%83%8c%e5%90%8e%ef%bc%8c%e7%9c%8bjerry%e4%b8%8ecarol%e5%a6%82%e4%bd%95%e7%94%a8%e7%ab%af%e7%b2%92%e9%85%b6%e6%8f%ad%e5%bc%80%e4%ba%ba%e7%b1%bb%e6%8a%97","status":"publish","type":"post","link":"https:\/\/www.nobelstars.cn\/?p=2946","title":{"rendered":"\u8bfa\u5956\u7ea7\u53d1\u73b0\u80cc\u540e\uff0c\u770bJerry\u4e0eCarol\u5982\u4f55\u7528\u7aef\u7c92\u9176\u63ed\u5f00\u4eba\u7c7b\u6297\u8870\u7684\u7ec8\u6781\u5e95\u724c"},"content":{"rendered":"
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\u7aef\u7c92\u7814\u7a76<\/span>\u5f00\u521b\u8005<\/strong>Prof. Jerry W. Shay<\/strong><\/p>\n
\"\"<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\u4ece\u53e4\u81f3\u4eca\uff0c\u8870\u8001\u4e00\u76f4\u662f\u4eba\u7c7b\u96be\u4ee5\u9003\u907f\u7684\u5bbf\u547d\uff0c\u4e5f\u662f\u8426\u7ed5\u5728\u5fc3\u5934\u6700\u6df1\u7684\u6050\u60e7\u3002\u5f53\u79e6\u59cb\u7687\u7edf\u4e00\u516d\u56fd\uff0c\u7ad9\u5728\u6743\u529b\u7684\u5dc5\u5cf0\uff0c\u5374\u60ca\u89c9\u65f6\u95f4\u7684\u6d41\u901d\u5bf9\u4ed6\u540c\u6837\u6beb\u4e0d\u7559\u60c5\uff0c\u4e8e\u662f\uff0c\u4ed6\u5f00\u542f\u4e86\u6c42\u4ed9\u4e4b\u65c5\uff0c\u6d3e\u5f90\u798f\u4e1c\u6e21\u5bfb\u627e\u957f\u751f\u4e0d\u8001\u836f\uff0c\u8017\u8d39\u65e0\u6570\u4eba\u529b\u7269\u529b\uff0c\u53ea\u4e3a\u4e86\u80fd\u6293\u4f4f\u90a3\u7f25\u7f08\u7684 \u201c\u6c38\u751f\u201d \u5e0c\u671b\u3002\u8fd9\u4e0d\u4ec5\u662f\u4ed6\u4e2a\u4eba\u7684\u6267\u5ff5\uff0c\u66f4\u662f\u4eba\u7c7b\u5bf9\u8870\u8001\u672c\u80fd\u6297\u62d2\u7684\u751f\u52a8\u5199\u7167\u3002\u6c49\u6b66\u5e1d\u540c\u6837\u75f4\u8ff7\u4e8e\u957f\u751f\uff0c\u5efa\u627f\u9732\u76d8\u627f\u63a5\u4ed9\u9732\uff0c\u5ba0\u4fe1\u65b9\u58eb\u70bc\u5236\u4e39\u836f\uff0c\u6700\u7ec8\u5374\u4e5f\u53ea\u80fd\u5728\u5c81\u6708\u9762\u524d\u4f4e\u5934 \u3002\u8870\u8001\uff0c\u8fd9\u4e2a\u795e\u79d8\u800c\u53c8\u5f3a\u5927\u7684\u529b\u91cf\uff0c\u5230\u5e95\u662f\u4ec0\u4e48\uff1f\u5b83\u7edd\u4e0d\u4ec5\u4ec5\u662f\u8138\u4e0a\u65e5\u76ca\u589e\u591a\u7684\u76b1\u7eb9\uff0c\u6216\u662f\u9010\u6e10\u82b1\u767d\u7684\u5934\u53d1\u90a3\u4e48\u7b80\u5355\u3002\u4ece\u751f\u7269\u5b66\u89d2\u5ea6\u6765\u770b\uff0c\u968f\u7740\u65f6\u95f4\u7684\u63a8\u79fb\uff0c\u6211\u4eec\u8eab\u4f53\u5185\u7684\u7ec6\u80de\u5982\u540c\u8001\u65e7\u7684\u673a\u5668\uff0c\u5f00\u59cb\u51fa\u73b0\u5404\u79cd\u95ee\u9898\u3002\u7ec6\u80de\u7684\u5206\u88c2\u80fd\u529b\u9010\u6e10\u4e0b\u964d\uff0c\u7ebf\u7c92\u4f53 \u2014\u2014\u00a0\u7ec6\u80de\u7684 \u201c\u80fd\u91cf\u5de5\u5382\u201d\uff0c\u529f\u80fd\u4e5f\u4e0d\u65ad\u8870\u9000\uff0c\u5bfc\u81f4\u80fd\u91cf\u4ea7\u751f\u4e0d\u8db3\u3002\u81ea\u7531\u57fa\u5728\u4f53\u5185\u8086\u610f\u6a2a\u884c\uff0c\u5bf9\u7ec6\u80de\u7684\u7ed3\u6784\u548c\u529f\u80fd\u9020\u6210\u4e25\u91cd\u7834\u574f\u3002\u800c\u9057\u4f20\u56e0\u7d20\u4e5f\u5728\u5176\u4e2d\u626e\u6f14\u7740\u5173\u952e\u89d2\u8272\uff0c\u67d0\u4e9b\u57fa\u56e0\u7a81\u53d8\u6216\u5f02\u5e38\u8868\u8fbe\uff0c\u4f1a\u50cf\u52a0\u901f\u952e\u4e00\u6837\uff0c\u8ba9\u8870\u8001\u7684\u8fdb\u7a0b\u5927\u5927\u63d0\u524d\u3002<\/strong>\u4e0d\u4ec5\u5982\u6b64\uff0c\u6211\u4eec\u751f\u6d3b\u7684\u73af\u5883\u3001\u65e5\u5e38\u7684\u751f\u6d3b\u4e60\u60ef\uff0c\u5982\u7d2b\u5916\u7ebf\u7684\u8fc7\u5ea6\u7167\u5c04\u3001\u7a7a\u6c14\u6c61\u67d3\u3001\u5438\u70df\u9157\u9152\u3001\u957f\u671f\u71ac\u591c\u7b49\uff0c\u4e5f\u90fd\u5728\u6084\u65e0\u58f0\u606f\u5730\u52a0\u901f\u7740\u8870\u8001\u7684\u811a\u6b65\u3002\u53ef\u4ee5\u8bf4\uff0c\u8870\u8001\u5c31\u50cf\u662f\u4e00\u573a\u7531\u5185\u800c\u5916\u3001\u591a\u56e0\u7d20\u4ea4\u7ec7\u7684\u590d\u6742 \u201c\u98ce\u66b4\u201d\uff0c\u5e2d\u5377\u7740\u6211\u4eec\u7684\u8eab\u4f53\u548c\u751f\u6d3b\u3002<\/strong><\/p>\n
\"\"<\/section>\n<\/section>\n<\/section>\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
<\/section>\n
<\/section>\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\n
\n
<\/section>\n
\n
\u7aef\u7c92\u9176\u7684\u53d1\u73b0<\/strong><\/section>\n<\/section>\n
\n
\n
\n
\n
\n
\n
\n
\u6539\u5199\u8870\u8001\u8ba4\u77e5\u7684\u8bfa\u5956\u6210\u679c<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
2009 \u5e74\uff0c\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u9881\u53d1\u7ed9\u4e86\u4f0a\u4e3d\u838e\u767d\u30fb\u5e03\u83b1\u514b\u672c\uff08Elizabeth H. Blackburn\uff09\u3001\u5361\u7f57\u5c14\u30fb\u683c\u96f7\u5fb7\uff08Carol W. Greider\uff09\u548c\u6770\u514b\u30fb\u7ecd\u65af\u5854\u514b\uff08Jack W. Szostak\uff09 \uff0c\u4ee5\u8868\u5f70\u4ed6\u4eec\u5728\u7aef\u7c92\u548c\u7aef\u7c92\u9176\u7814\u7a76\u9886\u57df\u7684\u6770\u51fa\u8d21\u732e\u3002<\/strong>\u8fd9\u4e00\u5956\u9879\u7684\u9881\u53d1\uff0c\u5982\u540c\u5728\u9ed1\u6697\u4e2d\u70b9\u4eae\u4e86\u4e00\u76cf\u660e\u706f\uff0c\u4e3a\u4eba\u7c7b\u6df1\u5165\u63a2\u7d22\u8870\u8001\u548c\u764c\u75c7\u7684\u5965\u79d8\u6307\u660e\u4e86\u65b9\u5411\u3002<\/section>\n
\n
\"\"<\/section>\n<\/section>\n
\u67d3\u8272\u4f53\u672b\u7aef\u7684\u7aef\u7c92\uff0c\u5c31\u50cf\u662f\u978b\u5e26\u4e24\u7aef\u7684\u5851\u6599\u5e3d\uff0c\u867d\u7136\u770b\u4f3c\u5fae\u4e0d\u8db3\u9053\uff0c\u5374\u5bf9\u67d3\u8272\u4f53\u7684\u7a33\u5b9a\u8d77\u7740\u81f3\u5173\u91cd\u8981\u7684\u4fdd\u62a4\u4f5c\u7528\u3002\u4f0a\u4e3d\u838e\u767d\u30fb\u5e03\u83b1\u514b\u672c\u548c\u6770\u514b\u30fb\u7ecd\u65af\u5854\u514b\u53d1\u73b0\uff0c\u7aef\u7c92 DNA \u5e8f\u5217\u80fd\u591f\u9632\u6b62\u67d3\u8272\u4f53\u5728\u7ec6\u80de\u5206\u88c2\u8fc7\u7a0b\u4e2d\u88ab\u964d\u89e3\uff0c\u7ef4\u6301\u67d3\u8272\u4f53\u7684\u5b8c\u6574\u6027\u3002<\/strong>\u800c\u5361\u7f57\u5c14\u30fb\u683c\u96f7\u5fb7\u548c\u4f0a\u4e3d\u838e\u767d\u30fb\u5e03\u83b1\u514b\u672c\u5219\u8fdb\u4e00\u6b65\u9274\u5b9a\u51fa\u4e86\u5408\u6210\u7aef\u7c92 DNA \u7684\u9176 \u2014\u2014 \u7aef\u7c92\u9176\uff0c\u63ed\u793a\u4e86\u7ec6\u80de\u7ef4\u6301\u7aef\u7c92\u957f\u5ea6\u7684\u795e\u79d8\u673a\u5236\u3002<\/strong><\/section>\n
<\/section>\n
\n
\"\"<\/section>\n<\/section>\n
\u5728\u6b63\u5e38\u7684\u7ec6\u80de\u5206\u88c2\u8fc7\u7a0b\u4e2d\uff0c\u7aef\u7c92\u4f1a\u50cf\u88ab\u78e8\u635f\u7684\u6a61\u76ae\u7b4b\u4e00\u6837\uff0c\u968f\u7740\u5206\u88c2\u6b21\u6570\u7684\u589e\u52a0\u800c\u9010\u6e10\u7f29\u77ed\u3002\u5f53\u7aef\u7c92\u7f29\u77ed\u5230\u4e00\u5b9a\u7a0b\u5ea6\u65f6\uff0c\u7ec6\u80de\u5c31\u4f1a\u6536\u5230 \u201c\u8870\u8001\u4fe1\u53f7\u201d\uff0c\u505c\u6b62\u5206\u88c2\uff0c\u8d70\u5411\u8870\u8001\u3002\u8fd9\u5c31\u50cf\u662f\u7ec6\u80de\u7684 \u201c\u751f\u547d\u65f6\u949f\u201d\uff0c\u7cbe\u51c6\u5730\u8bb0\u5f55\u7740\u7ec6\u80de\u7684\u5206\u88c2\u6b21\u6570\u548c\u5bff\u547d \u3002\u7136\u800c\uff0c\u7aef\u7c92\u9176\u7684\u51fa\u73b0\u6253\u7834\u4e86\u8fd9\u4e00\u5e38\u89c4\u3002\u7aef\u7c92\u9176\u80fd\u591f\u4ee5\u81ea\u8eab\u643a\u5e26\u7684 RNA \u4e3a\u6a21\u677f\uff0c\u5408\u6210\u7aef\u7c92 DNA\uff0c\u4e3a\u7f29\u77ed\u7684\u7aef\u7c92 \u201c\u6dfb\u7816\u52a0\u74e6\u201d\uff0c\u4ece\u800c\u7ef4\u6301\u7aef\u7c92\u7684\u957f\u5ea6\uff0c\u8ba9\u7ec6\u80de\u80fd\u591f\u7ee7\u7eed\u5206\u88c2\uff0c\u4fdd\u6301 \u201c\u5e74\u8f7b\u6d3b\u529b\u201d\u3002<\/strong><\/section>\n
\n
\"\"<\/section>\n<\/section>\n
\u8fd9\u4e00\u53d1\u73b0\u610f\u4e49\u91cd\u5927\uff0c\u5b83\u4e0d\u4ec5\u4ece\u5206\u5b50\u5c42\u9762\u63ed\u793a\u4e86\u8870\u8001\u8fc7\u7a0b\u4e2d\u9057\u4f20\u4fe1\u606f\u7684\u53d8\u5316\u673a\u5236\uff0c\u8ba9\u6211\u4eec\u5bf9\u8870\u8001\u7684\u672c\u8d28\u6709\u4e86\u66f4\u6df1\u523b\u7684\u8ba4\u8bc6\uff0c\u4e5f\u4e3a\u764c\u75c7\u7684\u7814\u7a76\u5e26\u6765\u4e86\u65b0\u7684\u66d9\u5149\u3002\u5728\u5927\u591a\u6570\u764c\u7ec6\u80de\u4e2d\uff0c\u7aef\u7c92\u9176\u5f02\u5e38\u6d3b\u8dc3\uff0c\u4f7f\u5f97\u764c\u7ec6\u80de\u80fd\u591f\u65e0\u9650\u589e\u6b96\uff0c\u9003\u907f\u8870\u8001\u548c\u6b7b\u4ea1\u7684\u547d\u8fd0\u3002\u56e0\u6b64\uff0c\u7aef\u7c92\u9176\u6210\u4e3a\u4e86\u6297\u764c\u836f\u7269\u7814\u53d1\u7684\u91cd\u8981\u9776\u70b9\uff0c\u4e3a\u653b\u514b\u764c\u75c7\u8fd9\u4e00\u96be\u9898\u63d0\u4f9b\u4e86\u65b0\u7684\u601d\u8def\u548c\u65b9\u6cd5\u3002<\/strong><\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n
\n
\n
01\u3001<\/strong><\/em>Prof. Jerry W. Shay \u6559\u6388<\/strong><\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\u6210\u957f\u4e0e\u5b66\u672f\u4e4b\u8def<\/strong><\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\"\"<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
<\/section>\n
\u5728\u7aef\u7c92\u9176\u7814\u7a76\u9886\u57df\uff0c\u6709\u4e00\u4f4d\u4e0d\u5f97\u4e0d\u63d0\u7684\u6770\u51fa\u4eba\u7269 \u2014\u2014Prof. Jerry W. Shay \u6559\u6388 \u3002\u4ed6\u5728\u8be5\u9886\u57df\u7684\u5353\u8d8a\u8d21\u732e\uff0c\u72b9\u5982\u7480\u74a8\u661f\u8fb0\uff0c\u7167\u4eae\u4e86\u65e0\u6570\u79d1\u7814\u5de5\u4f5c\u8005\u524d\u884c\u7684\u9053\u8def\u3002Jerry W. Shay \u6559\u6388\u51fa\u751f\u4e8e\u4e00\u4e2a\u5145\u6ee1\u6c42\u77e5\u6c1b\u56f4\u7684\u5bb6\u5ead\uff0c\u7236\u6bcd\u5bf9\u77e5\u8bc6\u7684\u70ed\u7231\u548c\u8ffd\u6c42\uff0c\u5728\u4ed6\u5e7c\u5c0f\u7684\u5fc3\u7075\u4e2d\u79cd\u4e0b\u4e86\u63a2\u7d22\u79d1\u5b66\u7684\u79cd\u5b50 \u3002\u5b66\u751f\u65f6\u4ee3\uff0c\u4ed6\u5c31\u5c55\u73b0\u51fa\u4e86\u5bf9\u751f\u7269\u5b66\u7684\u6d53\u539a\u5174\u8da3\uff0c\u7ecf\u5e38\u6c89\u6d78\u5728\u56fe\u4e66\u9986\u7684\u751f\u7269\u4e66\u7c4d\u4e2d\uff0c\u63a2\u7d22\u751f\u547d\u7684\u5965\u79d8 \u3002\u51ed\u501f\u7740\u4f18\u5f02\u7684\u6210\u7ee9\u548c\u5bf9\u751f\u7269\u5b66\u7684\u6267\u7740\u70ed\u7231\uff0c\u4ed6\u987a\u5229\u8fdb\u5165\u4e86\u77e5\u540d\u5b66\u5e9c\uff0c\u5f00\u542f\u4e86\u4ed6\u5728\u7ec6\u80de\u751f\u7269\u5b66\u9886\u57df\u7684\u6c42\u5b66\u4e4b\u65c5\u3002<\/p>\n<\/section>\n
\n
\"\"<\/section>\n<\/section>\n
\u5728\u5927\u5b66\u671f\u95f4\uff0cJerry W. Shay \u6559\u6388\u5982\u9965\u4f3c\u6e34\u5730\u6c72\u53d6\u7740\u77e5\u8bc6\u7684\u517b\u5206 \u3002\u4ed6\u79ef\u6781\u53c2\u4e0e\u5404\u79cd\u7ec6\u80de\u751f\u7269\u5b66\u5b9e\u9a8c\u8bfe\u7a0b\uff0c\u5728\u663e\u5fae\u955c\u4e0b\u89c2\u5bdf\u7ec6\u80de\u7684\u5f62\u6001\u548c\u5206\u88c2\u8fc7\u7a0b\uff0c\u4eff\u4f5b\u6253\u5f00\u4e86\u4e00\u6247\u901a\u5f80\u5fae\u89c2\u4e16\u754c\u7684\u5927\u95e8\uff0c\u8ba9\u4ed6\u6df1\u6df1\u7740\u8ff7\u3002\u4ed6\u8fd8\u4e3b\u52a8\u52a0\u5165\u4e86\u5b66\u6821\u7684\u79d1\u7814\u5c0f\u7ec4\uff0c\u8ddf\u968f\u5bfc\u5e08\u53c2\u4e0e\u7ec6\u80de\u8870\u8001\u76f8\u5173\u7684\u7814\u7a76\u9879\u76ee\u3002\u5728\u8fd9\u4e2a\u8fc7\u7a0b\u4e2d\uff0c\u4ed6\u4e0d\u4ec5\u638c\u63e1\u4e86\u624e\u5b9e\u7684\u5b9e\u9a8c\u6280\u80fd\uff0c\u66f4\u57f9\u517b\u4e86\u654f\u9510\u7684\u79d1\u7814\u6d1e\u5bdf\u529b\u548c\u4e25\u8c28\u7684\u79d1\u5b66\u601d\u7ef4\u3002\u7814\u7a76\u751f\u9636\u6bb5\uff0cJerry W. Shay \u6559\u6388\u5c06\u7814\u7a76\u65b9\u5411\u805a\u7126\u5728\u4e86\u7aef\u7c92\u548c\u7aef\u7c92\u9176\u4e0a\u3002\u5f53\u65f6\uff0c\u7aef\u7c92\u548c\u7aef\u7c92\u9176\u7684\u7814\u7a76\u8fd8\u5904\u4e8e\u8d77\u6b65\u9636\u6bb5\uff0c\u8bb8\u591a\u673a\u5236\u5c1a\u4e0d\u660e\u786e\uff0c\u4f46\u4ed6\u575a\u4fe1\u8fd9\u4e2a\u9886\u57df\u8574\u542b\u7740\u5de8\u5927\u7684\u6f5c\u529b\uff0c\u80fd\u591f\u4e3a\u4eba\u7c7b\u63ed\u793a\u8870\u8001\u548c\u764c\u75c7\u7684\u5965\u79d8\u3002<\/strong>\u4ed6\u4e00\u5934\u624e\u8fdb\u5b9e\u9a8c\u5ba4\uff0c\u6bcf\u5929\u90fd\u82b1\u8d39\u5927\u91cf\u65f6\u95f4\u8fdb\u884c\u5b9e\u9a8c\u64cd\u4f5c\u548c\u6570\u636e\u5206\u6790 \u3002\u4e3a\u4e86\u83b7\u53d6\u51c6\u786e\u7684\u5b9e\u9a8c\u7ed3\u679c\uff0c\u4ed6\u5e38\u5e38\u5728\u5b9e\u9a8c\u5ba4\u91cc\u4e00\u5f85\u5c31\u662f\u5341\u51e0\u4e2a\u5c0f\u65f6\uff0c\u5fd8\u8bb0\u4e86\u65f6\u95f4\u7684\u6d41\u901d\u3002<\/p>\n<\/section>\n
\n
\"\"<\/section>\n<\/section>\n
\u5728\u7814\u7a76\u8fc7\u7a0b\u4e2d\uff0cJerry W. Shay \u6559\u6388\u9762\u4e34\u7740\u8bf8\u591a\u6311\u6218\u3002\u5b9e\u9a8c\u6280\u672f\u7684\u4e0d\u6210\u719f\u3001\u5b9e\u9a8c\u7ed3\u679c\u7684\u4e0d\u7a33\u5b9a\uff0c\u90fd\u66fe\u8ba9\u4ed6\u9677\u5165\u56f0\u5883\u3002\u4f46\u4ed6\u4ece\u672a\u653e\u5f03\uff0c\u51ed\u501f\u7740\u575a\u5b9a\u7684\u4fe1\u5ff5\u548c\u987d\u5f3a\u7684\u6bc5\u529b\uff0c\u4e0d\u65ad\u5c1d\u8bd5\u65b0\u7684\u5b9e\u9a8c\u65b9\u6cd5\u548c\u6280\u672f \u3002\u4ed6\u79ef\u6781\u4e0e\u56fd\u5185\u5916\u7684\u79d1\u7814\u56e2\u961f\u4ea4\u6d41\u5408\u4f5c\uff0c\u5206\u4eab\u81ea\u5df1\u7684\u7814\u7a76\u6210\u679c\u548c\u7ecf\u9a8c\uff0c\u540c\u65f6\u4e5f\u5b66\u4e60\u501f\u9274\u4ed6\u4eba\u7684\u5148\u8fdb\u6280\u672f\u548c\u7406\u5ff5 \u3002\u7ecf\u8fc7\u591a\u5e74\u7684\u4e0d\u61c8\u52aa\u529b\uff0c\u4ed6\u5728\u7aef\u7c92\u548c\u7aef\u7c92\u9176\u7814\u7a76\u9886\u57df\u53d6\u5f97\u4e86\u4e00\u7cfb\u5217\u91cd\u8981\u6210\u679c\u3002<\/strong>\u4ed6\u9996\u6b21\u63ed\u793a\u4e86\u7aef\u7c92\u9176\u5728\u80bf\u7624\u7ec6\u80de\u4e2d\u7684\u5f02\u5e38\u6fc0\u6d3b\u673a\u5236\uff0c\u53d1\u73b0\u80bf\u7624\u7ec6\u80de\u80fd\u591f\u901a\u8fc7\u6fc0\u6d3b\u7aef\u7c92\u9176\u6765\u7ef4\u6301\u7aef\u7c92\u7684\u957f\u5ea6\uff0c\u4ece\u800c\u5b9e\u73b0\u65e0\u9650\u589e\u6b96 \u3002\u8fd9\u4e00\u53d1\u73b0\u4e3a\u764c\u75c7\u7684\u8bca\u65ad\u548c\u6cbb\u7597\u63d0\u4f9b\u4e86\u65b0\u7684\u9776\u70b9\u548c\u601d\u8def \u3002\u4ed6\u8fd8\u6df1\u5165\u7814\u7a76\u4e86\u7aef\u7c92\u9176\u4e0e\u7ec6\u80de\u8870\u8001\u7684\u5173\u7cfb\uff0c\u53d1\u73b0\u7aef\u7c92\u9176\u7684\u6d3b\u6027\u7f3a\u5931\u4f1a\u52a0\u901f\u7ec6\u80de\u7684\u8870\u8001\u8fdb\u7a0b \u3002\u901a\u8fc7\u4e00\u7cfb\u5217\u521b\u65b0\u6027\u7684\u5b9e\u9a8c\uff0c\u4ed6\u63d0\u51fa\u4e86 \u201c\u7aef\u7c92\u9176\u8c03\u63a7\u7ec6\u80de\u8870\u8001\u548c\u764c\u53d8\u7684\u5206\u5b50\u6a21\u578b\u201d\uff0c\u8fd9\u4e00\u6a21\u578b\u4e3a\u7406\u89e3\u7ec6\u80de\u7684\u751f\u547d\u5386\u7a0b\u63d0\u4f9b\u4e86\u91cd\u8981\u7684\u6846\u67b6\u3002<\/strong><\/p>\n

Jerry W. Shay \u6559\u6388\u7684\u7814\u7a76\u6210\u679c\u5728\u5b66\u672f\u754c\u5f15\u8d77\u4e86\u5e7f\u6cdb\u5173\u6ce8\u548c\u9ad8\u5ea6\u8bc4\u4ef7 \u3002\u4ed6\u53d1\u8868\u4e86\u5927\u91cf\u9ad8\u8d28\u91cf\u7684\u5b66\u672f\u8bba\u6587\uff0c\u5176\u4e2d\u591a\u7bc7\u8bba\u6587\u53d1\u8868\u5728\u300aCell\u300b\u300aNature\u300b\u300aScience\u300b\u7b49\u56fd\u9645\u9876\u5c16\u5b66\u672f\u671f\u520a\u4e0a \u3002<\/strong>\u4ed6\u7684\u7814\u7a76\u6210\u679c\u88ab\u5e7f\u6cdb\u5f15\u7528\uff0c\u4e3a\u7aef\u7c92\u548c\u7aef\u7c92\u9176\u9886\u57df\u7684\u53d1\u5c55\u505a\u51fa\u4e86\u91cd\u8981\u8d21\u732e \u3002\u4ed6\u4e5f\u56e0\u6b64\u6210\u4e3a\u4e86\u7aef\u7c92\u548c\u7aef\u7c92\u9176\u7814\u7a76\u9886\u57df\u7684\u6743\u5a01\u4eba\u7269\uff0c\u5438\u5f15\u4e86\u4f17\u591a\u79d1\u7814\u5de5\u4f5c\u8005\u524d\u6765\u5b66\u4e60\u548c\u5408\u4f5c\u3002<\/p>\n<\/section>\n

\n
\"\"<\/section>\n<\/section>\n
<\/section>\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\u4e2a\u4eba\u4ecb\u7ecd<\/strong><\/section>\n<\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n
<\/section>\n
\ud83c\udfeb\u6240\u5728\u673a\u6784<\/strong>The University of Texas Southwestern Medical Center, Dallas \u5fb7\u514b\u8428\u65af\u5927\u5b66\u897f\u5357\u533b\u5b66\u4e2d\u5fc3\uff08\u8fbe\u62c9\u65af\uff09<\/p>\n

Professor of Cell Biology \u7ec6\u80de\u751f\u7269\u5b66\u6559\u6388<\/p>\n

Vice Chair of Cell Biology Department \u7ec6\u80de\u751f\u7269\u5b66\u7cfb\u526f\u4e3b\u4efb<\/p>\n

Associate Director of the NCI\u2011designated Harold Simmons Comprehensive Cancer Center \u7f8e\u56fd\u56fd\u5bb6\u764c\u75c7\u7814\u7a76\u6240\uff08NCI\uff09\u6307\u5b9a\u7684\u54c8\u7f57\u5fb7\u00b7\u897f\u8499\u65af\u7efc\u5408\u764c\u75c7\u4e2d\u5fc3\u526f\u4e3b\u4efb<\/p>\n

\ud83d\udd2c \u7814\u7a76\u9886\u57df\u4e0e\u91cd\u70b9<\/strong><\/p>\n

\u7aef\u7c92\u4e0e\u7aef\u7c92\u9176<\/span>\uff08telomeres & telomerase\uff09\uff1a\u63a2\u7a76\u5b83\u4eec\u5728\u7ec6\u80de\u8001\u5316\uff08senescence\uff09\u548c\u764c\u75c7\u4e2d\u7684\u6838\u5fc3\u4f5c\u7528<\/p>\n

\u7aef\u7c92\u9176\u4f5c\u4e3a\u764c\u75c7\u751f\u7269\u6807\u5fd7\u7269\u4e0e\u6cbb\u7597\u9776\u70b9\uff1a\u957f\u671f\u7814\u7a76telomerase<\/span>\u5728\u764c\u7ec6\u80de\u65e0\u9650\u589e\u6b96\u4e2d\u7684\u5173\u952e\u4f5c\u7528\uff0c\u5bf9\u5e94\u7684\u6291\u5236\u5242\u5df2\u8fdb\u5165\u4e34\u5e8a\u5b9e\u9a8c\u9636\u6bb5<\/p>\n

\u7aef\u7c92\u957f\u5ea6\u8c03\u63a7\u673a\u5236\uff1a\u7814\u7a76\u7aef\u7c92\u957f\u5ea6\u5982\u4f55\u5f71\u54cd\u57fa\u56e0\u8868\u8fbe\u53ca\u8870\u8001\u8fc7\u7a0b<\/p>\n

\ud83c\udfc6 \u5b66\u672f\u6210\u5c31\u4e0e\u8363\u8a89<\/strong><\/p>\n

\u51fa\u7248\u8d85\u8fc7650\u7bc7\u8bba\u6587\uff0c\u88ab\u5f15\u7528\u8d85\u8fc715,000\u6b21\uff0ch-index \u8d85\u8fc7130<\/p>\n

\u5f00\u521b\u6027\u8bba\u6587\u5305\u62ec\uff1a<\/p>\n

\u300aSpecific association of human telomerase activity with immortal cells and cancer\u300b\uff0cScience\uff0c\u7ea6\u202f9,900\u6b21\u5f15\u7528<\/p>\n

\u300aExtension of life\u2011span by introduction of telomerase into normal human cells\u300b\uff0cScience\uff0c\u7ea6\u202f5,100\u6b21\u5f15\u7528<\/p>\n

\u300aA survey of telomerase activity in human cancer\u300b\uff0cEur J Cancer\uff0c\u7ea6\u202f2,900\u6b21\u5f15\u7528<\/p>\n

\u5956\u9879\u8363\u8a89\uff1a<\/strong><\/p>\n

Research.com \u201cMolecular Biology U.S. Leader\u201d (2023\u20132025) \u7f8e\u56fd\u5206\u5b50\u751f\u7269\u5b66\u9886\u57df\u9886\u519b\u4eba\u7269<\/p>\n

American Aging Association Hayflick Award \u7f8e\u56fd\u8870\u8001\u534f\u4f1a Hayflick \u5956 \u7b49\u591a\u4e2a\u56fd\u9645\u5b66\u672f\u5956\u9879<\/p>\n

\u4ea7\u4e1a\u8d21\u732e\uff1a<\/strong><\/p>\n

\u5171\u540c\u521b\u7acb Geron Corporation\uff08\u9996\u5bb6\u5f00\u53d1 telomerase \u6cbb\u7597\u7684\u516c\u53f8\uff09<\/p>\n

\u662f\u591a\u5bb6\u751f\u7269\u79d1\u6280\u516c\u53f8\uff08\u5982 Life Length\uff09\u79d1\u5b66\u987e\u95ee\u4e0e\u4e13\u5229\u53d1\u660e\u4eba<\/p>\n

\u2705 \u603b\u7ed3<\/strong><\/p>\n

Prof. Shay \u7684\u6838\u5fc3\u4f18\u52bf\u5728\u4e8e\u5c06\u7aef\u7c92\u9176\u7684\u57fa\u7840\u673a\u5236\u7814\u7a76\u4e0e\u764c\u75c7\u6cbb\u7597\u7d27\u5bc6\u7ed3\u5408\uff0c\u662f\u8be5\u9886\u57df\u4e2d\u7f55\u89c1\u7684\u517c\u5177\u79d1\u5b66\u6df1\u5ea6\u4e0e\u8f6c\u5316\u4ef7\u503c\u7684\u9876\u5c16\u79d1\u5b66\u5bb6\u3002\u4ed6\u7684\u56e2\u961f\u4e0d\u4ec5\u53d1\u73b0 telomerase \u7684\u751f\u7269\u5b66\u4f5c\u7528\uff0c\u8fd8\u63a8\u52a8\u76f8\u5173\u836f\u7269\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4f7f\u5176\u5728\u5b66\u672f\u754c\u548c\u4ea7\u4e1a\u754c\u5747\u62e5\u6709\u5e7f\u6cdb\u5f71\u54cd\u529b\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
<\/section>\n<\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\n
\n
\n
02\u3001<\/strong><\/em>\u79d1\u7814\u6210\u679c\uff0c<\/strong>\u6539\u53d8\u4e16\u754c\u00a0<\/strong><\/section>\n<\/section>\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\"\"<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
<\/section>\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\u7aef\u7c92\u957f\u5ea6\u68c0\u6d4b<\/span>\u65b0\u65b9\u6cd5<\/strong><\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\u5728\u7aef\u7c92\u7814\u7a76\u9886\u57df\uff0c\u51c6\u786e\u6d4b\u91cf\u7aef\u7c92\u957f\u5ea6\u4e00\u76f4\u662f\u5173\u952e\u4e14\u5177\u6709\u6311\u6218\u6027\u7684\u4efb\u52a1\u3002\u4f20\u7edf\u7684\u7aef\u7c92\u957f\u5ea6\u68c0\u6d4b\u65b9\u6cd5\u5b58\u5728\u8bf8\u591a\u5c40\u9650\u6027\uff0c\u5176\u4e2d\u653e\u5c04\u6027\u63a2\u9488<\/span>\u867d\u7136\u5728\u65e9\u671f\u7684\u7814\u7a76\u4e2d\u88ab\u5e7f\u6cdb\u5e94\u7528\uff0c\u4f46\u5b83\u5c31\u50cf\u4e00\u9897\u4e0d\u7a33\u5b9a\u7684 \u201c\u5b9a\u65f6\u70b8\u5f39\u201d\uff0c\u5b58\u5728\u8bf8\u591a\u9690\u60a3\u3002\u653e\u5c04\u6027\u7269\u8d28\u7684\u4e0d\u7a33\u5b9a\u6027\u4f7f\u5f97\u5b9e\u9a8c\u7ed3\u679c\u96be\u4ee5\u7a33\u5b9a\u91cd\u590d\uff0c\u7814\u7a76\u4eba\u5458\u5e38\u5e38\u4e3a\u4e86\u83b7\u5f97\u51c6\u786e\u7684\u6570\u636e\uff0c\u4e0d\u5f97\u4e0d\u53cd\u590d\u8fdb\u884c\u5b9e\u9a8c\uff0c\u8017\u8d39\u5927\u91cf\u7684\u65f6\u95f4\u548c\u7cbe\u529b\u3002\u800c\u4e14\uff0c\u5904\u7406\u8fd9\u4e9b\u653e\u5c04\u6027\u7269\u8d28\u9700\u8981\u7279\u6b8a\u7684\u9632\u62a4\u8bbe\u5907\u548c\u4e25\u683c\u7684\u64cd\u4f5c\u6d41\u7a0b\uff0c\u4e00\u65e6\u64cd\u4f5c\u4e0d\u5f53\uff0c\u5c31\u53ef\u80fd\u5bf9\u5b9e\u9a8c\u4eba\u5458\u7684\u8eab\u4f53\u5065\u5eb7\u9020\u6210\u4e25\u91cd\u5371\u5bb3 \u3002\u968f\u7740\u6280\u672f\u7684\u53d1\u5c55\uff0c\u975e\u653e\u5c04\u6027\u65b9\u6cd5\u9010\u6e10\u5174\u8d77\uff0c\u4f46\u4e5f\u5e76\u975e\u5c3d\u5584\u5c3d\u7f8e \u3002\u4f8b\u5982\uff0c\u5e38\u7528\u7684 DIG\uff08digoxigenin\uff09\u63a2\u9488\u975e\u653e\u5c04\u6027\u65b9\u6cd5\uff0c\u5c31\u50cf\u662f\u4e00\u4e2a\u7075\u654f\u5ea6\u6b20\u4f73\u7684 \u201c\u63a2\u6d4b\u5668\u201d\u3002\u5b83\u9700\u8981\u76f8\u5bf9\u8f83\u591a\u7684\u57fa\u56e0\u7ec4 DNA \u624d\u80fd\u8fdb\u884c\u6709\u6548\u7684\u68c0\u6d4b\uff0c\u8fd9\u5728\u4e00\u4e9b\u6837\u672c\u7a00\u7f3a\u7684\u7814\u7a76\u4e2d\uff0c\u5c31\u6210\u4e86\u4e00\u4e2a\u96be\u4ee5\u8de8\u8d8a\u7684\u969c\u788d \u3002\u800c\u4e14\uff0c\u5176\u7075\u654f\u6027\u8f83\u5dee\uff0c\u5bf9\u4e8e\u4e00\u4e9b\u7ec6\u5fae\u7684\u7aef\u7c92\u957f\u5ea6\u53d8\u5316\uff0c\u5f80\u5f80\u96be\u4ee5\u51c6\u786e\u6355\u6349\uff0c\u5c31\u5982\u540c\u5728\u9ed1\u6697\u4e2d\u5bfb\u627e\u5fae\u5f31\u7684\u661f\u5149\uff0c\u5e38\u5e38\u4f1a\u9519\u5931\u91cd\u8981\u7684\u4fe1\u606f\u3002<\/p>\n<\/section>\n
\n
\"\"<\/section>\n<\/section>\n
\u4e3a\u4e86\u7a81\u7834\u8fd9\u4e9b\u56f0\u5883\uff0cProf. Jerry W. Shay \u6559\u6388\u5e26\u9886\u4ed6\u7684\u56e2\u961f\uff0c\u5f00\u542f\u4e86\u4e00\u573a\u8270\u82e6\u7684\u79d1\u7814\u653b\u5173 \u3002\u4ed6\u4eec\u6df1\u5165\u7814\u7a76\u7aef\u7c92\u7684\u7ed3\u6784\u548c\u7279\u6027\uff0c\u4ece\u5206\u5b50\u5c42\u9762\u5bfb\u627e\u65b0\u7684\u68c0\u6d4b\u601d\u8def \u3002\u7ecf\u8fc7\u65e0\u6570\u6b21\u7684\u5b9e\u9a8c\u5c1d\u8bd5\u548c\u6570\u636e\u5206\u6790\uff0c\u4ed6\u4eec\u7ec8\u4e8e\u5f00\u53d1\u51fa\u4e86\u4e00\u79cd\u65b0\u578b\u975e\u653e\u5c04\u6027\u65b9\u6cd5 \u3002\u8fd9\u79cd\u65b9\u6cd5\u5c31\u50cf\u662f\u4e3a\u7aef\u7c92\u68c0\u6d4b\u91cf\u8eab\u5b9a\u5236\u7684 \u201c\u7cbe\u5bc6\u4eea\u5668\u201d\uff0c\u4f7f\u7528\u591a\u4e2a DIG \u5206\u5b50\uff0c\u5de7\u5999\u5730\u589e\u5f3a\u4e86\u7075\u654f\u6027\u548c\u7aef\u7c92\u68c0\u6d4b\u7684\u7a33\u5b9a\u6027\u3002<\/strong>\u591a\u4e2a DIG \u5206\u5b50\u7684\u8fd0\u7528\uff0c\u5c31\u50cf\u662f\u7ed9\u7aef\u7c92\u68c0\u6d4b\u52a0\u4e0a\u4e86\u4e00\u4e2a \u201c\u4fe1\u53f7\u653e\u5927\u5668\u201d \u3002\u5b83\u4eec\u80fd\u591f\u4e0e\u7aef\u7c92 DNA \u66f4\u7d27\u5bc6\u3001\u66f4\u7279\u5f02\u6027\u5730\u7ed3\u5408\uff0c\u4ece\u800c\u5927\u5927\u63d0\u9ad8\u4e86\u68c0\u6d4b\u7684\u7075\u654f\u6027 \u3002\u5373\u4f7f\u662f\u6781\u5176\u5fae\u5c0f\u7684\u7aef\u7c92\u957f\u5ea6\u53d8\u5316\uff0c\u4e5f\u80fd\u88ab\u7cbe\u51c6\u5730\u68c0\u6d4b\u5230 \u3002\u540c\u65f6\uff0c\u8fd9\u79cd\u65b9\u6cd5\u8fd8\u63d0\u9ad8\u4e86\u68c0\u6d4b\u7684\u7a33\u5b9a\u6027\uff0c\u4f7f\u5f97\u5b9e\u9a8c\u7ed3\u679c\u66f4\u52a0\u53ef\u9760\uff0c\u51cf\u5c11\u4e86\u8bef\u5dee\u7684\u5e72\u6270 \u3002\u5c31\u50cf\u4e3a\u7aef\u7c92\u68c0\u6d4b\u5efa\u7acb\u4e86\u4e00\u4e2a\u575a\u56fa\u7684 \u201c\u57fa\u77f3\u201d\uff0c\u8ba9\u7814\u7a76\u4eba\u5458\u80fd\u591f\u5728\u66f4\u7a33\u5b9a\u7684\u57fa\u7840\u4e0a\u8fdb\u884c\u6df1\u5165\u7814\u7a76\u3002<\/p>\n

\u8fd9\u9879\u6210\u679c\u7684\u610f\u4e49\u975e\u51e1\uff0c\u5b83\u4e3a\u8870\u8001\u548c\u764c\u75c7\u7814\u7a76\u63d0\u4f9b\u4e86\u5f3a\u6709\u529b\u7684\u5de5\u5177\u3002<\/strong>\u5728\u8870\u8001\u7814\u7a76\u4e2d\uff0c\u79d1\u5b66\u5bb6\u4eec\u53ef\u4ee5\u901a\u8fc7\u51c6\u786e\u6d4b\u91cf\u7aef\u7c92\u957f\u5ea6\u7684\u53d8\u5316\uff0c\u66f4\u6df1\u5165\u5730\u4e86\u89e3\u8870\u8001\u7684\u8fdb\u7a0b\u548c\u673a\u5236 \u3002\u5c31\u50cf\u4e3a\u8870\u8001\u7814\u7a76\u6253\u5f00\u4e86\u4e00\u6247\u65b0\u7684\u7a97\u6237\uff0c\u8ba9\u6211\u4eec\u80fd\u591f\u66f4\u6e05\u6670\u5730\u770b\u5230\u8870\u8001\u8fc7\u7a0b\u4e2d\u7ec6\u80de\u5185\u90e8\u7684\u53d8\u5316 \u3002\u5728\u764c\u75c7\u7814\u7a76\u4e2d\uff0c\u7aef\u7c92\u957f\u5ea6\u7684\u51c6\u786e\u68c0\u6d4b\u53ef\u4ee5\u5e2e\u52a9\u533b\u751f\u66f4\u51c6\u786e\u5730\u8bca\u65ad\u764c\u75c7\uff0c\u8bc4\u4f30\u764c\u75c7\u7684\u53d1\u5c55\u9636\u6bb5\u548c\u9884\u540e \u3002\u4f8b\u5982\uff0c\u901a\u8fc7\u68c0\u6d4b\u764c\u7ec6\u80de\u4e2d\u7aef\u7c92\u957f\u5ea6\u7684\u5f02\u5e38\u53d8\u5316\uff0c\u533b\u751f\u53ef\u4ee5\u66f4\u65e9\u5730\u53d1\u73b0\u764c\u75c7\u7684\u8ff9\u8c61\uff0c\u4e3a\u60a3\u8005\u5236\u5b9a\u66f4\u7cbe\u51c6\u7684\u6cbb\u7597\u65b9\u6848 \u3002\u5b83\u8fd8\u4e3a\u6297\u764c\u836f\u7269\u7684\u7814\u53d1\u63d0\u4f9b\u4e86\u91cd\u8981\u7684\u53c2\u8003\u4f9d\u636e\uff0c\u6709\u52a9\u4e8e\u5f00\u53d1\u51fa\u66f4\u6709\u6548\u7684\u6297\u764c\u836f\u7269\uff0c\u4e3a\u764c\u75c7\u60a3\u8005\u5e26\u6765\u65b0\u7684\u5e0c\u671b\u3002<\/p>\n<\/section>\n

\n
\"\"<\/section>\n<\/section>\n
<\/section>\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\u9776\u5411\u764c\u7ec6\u80de\u7684\u7aef\u7c92\u7814\u7a76<\/strong><\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\u764c\u7ec6\u80de\uff0c\u8fd9\u4e2a\u4eba\u7c7b\u5065\u5eb7\u7684 \u201c\u5934\u53f7\u6740\u624b\u201d\uff0c\u4e00\u76f4\u4ee5\u6765\u90fd\u662f\u533b\u5b66\u7814\u7a76\u7684\u91cd\u70b9\u5bf9\u8c61 \u3002\u5b83\u4e4b\u6240\u4ee5\u5982\u6b64\u96be\u4ee5\u653b\u514b\uff0c\u4e00\u4e2a\u91cd\u8981\u7684\u539f\u56e0\u5c31\u5728\u4e8e\u5176\u72ec\u7279\u7684\u7aef\u7c92\u673a\u5236\u3002\u4e0e\u6b63\u5e38\u7ec6\u80de\u4e0d\u540c\uff0c\u764c\u7ec6\u80de\u4e2d\u7684\u7aef\u7c92\u5c31\u50cf\u88ab\u65bd\u4e86\u9b54\u6cd5\u4e00\u6837\uff0c\u4e0d\u4f1a\u968f\u7740\u7ec6\u80de\u5206\u88c2\u800c\u7f29\u77ed \u3002\u8fd9\u80cc\u540e\u7684 \u201c\u529f\u81e3\u201d \u5c31\u662f\u7aef\u7c92\u9176\uff0c\u5b83\u5728\u764c\u7ec6\u80de\u4e2d\u5f02\u5e38\u6d3b\u8dc3\uff0c\u80fd\u591f\u6301\u7eed\u4e3a\u7aef\u7c92\u8865\u5145 DNA \u5e8f\u5217\uff0c\u8ba9\u7aef\u7c92\u59cb\u7ec8\u4fdd\u6301\u5728\u8db3\u591f\u7684\u957f\u5ea6\uff0c\u4ece\u800c\u4f7f\u5f97\u764c\u7ec6\u80de\u80fd\u591f\u9003\u8131\u8870\u8001\u548c\u6b7b\u4ea1\u7684\u547d\u8fd0\uff0c\u5b9e\u73b0\u65e0\u9650\u589e\u6b96 \u3002\u8fd9\u79cd\u65e0\u9650\u589e\u6b96\u7684\u80fd\u529b\uff0c\u4f7f\u5f97\u764c\u7ec6\u80de\u80fd\u591f\u5728\u4f53\u5185\u75af\u72c2\u751f\u957f\uff0c\u4e0d\u65ad\u4fb5\u88ad\u548c\u7834\u574f\u5468\u56f4\u7684\u6b63\u5e38\u7ec4\u7ec7\u548c\u5668\u5b98\uff0c\u7ed9\u60a3\u8005\u7684\u751f\u547d\u5065\u5eb7\u5e26\u6765\u5de8\u5927\u5a01\u80c1\u3002Prof. Jerry W. Shay \u6559\u6388\u5bf9\u764c\u7ec6\u80de\u7684\u7aef\u7c92\u673a\u5236\u5c55\u5f00\u4e86\u6df1\u5165\u7814\u7a76 \u3002\u4ed6\u5c31\u50cf\u4e00\u4f4d\u52c7\u6562\u7684\u63a2\u9669\u5bb6\uff0c\u6df1\u5165\u5230\u764c\u7ec6\u80de\u7684\u5fae\u89c2\u4e16\u754c\u4e2d\uff0c\u5bfb\u627e\u5bf9\u6297\u5b83\u7684 \u201c\u79d8\u5bc6\u6b66\u5668\u201d \u3002\u7ecf\u8fc7\u591a\u5e74\u7684\u6f5c\u5fc3\u7814\u7a76\uff0c\u4ed6\u53d1\u73b0\u4e86\u4e00\u79cd\u540d\u4e3a 6 – thiodg \u7684\u5c0f\u5206\u5b50\uff0c\u5b83\u5c31\u50cf\u662f\u4e00\u628a\u4e13\u95e8\u9488\u5bf9\u764c\u7ec6\u80de\u7684 \u201c\u7cbe\u51c6\u624b\u672f\u5200\u201d\u3002<\/strong><\/p>\n<\/section>\n
\n
\"\"<\/section>\n<\/section>\n
6 – thiodg \u80fd\u591f\u7cbe\u51c6\u5730\u5b9a\u4f4d\u7ec6\u80de\u7684 \u201c\u751f\u7269\u949f\u201d\u2014\u2014 \u7aef\u7c92\u3002\u5b83\u7684\u4f5c\u7528\u673a\u5236\u5341\u5206\u5de7\u5999\uff0c\u5f53\u5b83\u8fdb\u5165\u764c\u7ec6\u80de\u540e\uff0c\u4f1a\u5e72\u6270\u764c\u7ec6\u80de\u4e2d\u7ef4\u6301\u7aef\u7c92\u957f\u5ea6\u7684\u6b63\u5e38\u9014\u5f84\u3002<\/strong>\u5c31\u50cf\u5728\u764c\u7ec6\u80de\u7684 \u201c\u751f\u4ea7\u7ebf\u201d \u4e0a\u8bbe\u7f6e\u4e86\u969c\u788d\uff0c\u963b\u6b62\u7aef\u7c92\u9176\u6b63\u5e38\u5de5\u4f5c\uff0c\u4f7f\u5f97\u7aef\u7c92\u65e0\u6cd5\u5f97\u5230\u53ca\u65f6\u7684\u4fee\u590d\u548c\u5ef6\u957f \u3002\u968f\u7740\u7ec6\u80de\u7684\u4e0d\u65ad\u5206\u88c2\uff0c\u7aef\u7c92\u9010\u6e10\u7f29\u77ed\uff0c\u5f53\u7f29\u77ed\u5230\u4e34\u754c\u957f\u5ea6\u65f6\uff0c\u764c\u7ec6\u80de\u5c31\u4f1a\u6536\u5230 \u201c\u6b7b\u4ea1\u4fe1\u53f7\u201d\uff0c\u65e0\u6cd5\u518d\u7ee7\u7eed\u5206\u88c2\uff0c\u6700\u7ec8\u8d70\u5411\u51cb\u4ea1\u3002\u66f4\u4e3a\u91cd\u8981\u7684\u662f\uff0c6 – thiodg \u5728\u53d1\u6325\u6297\u764c\u4f5c\u7528\u7684\u540c\u65f6\uff0c\u51e0\u4e4e\u6ca1\u6709\u4e25\u91cd\u7684\u8840\u6db2\u526f\u4f5c\u7528\u3002\u5728\u4f20\u7edf\u7684\u764c\u75c7\u6cbb\u7597\u4e2d\uff0c\u8bb8\u591a\u6297\u764c\u836f\u7269\u5728\u6740\u6b7b\u764c\u7ec6\u80de\u7684\u540c\u65f6\uff0c\u4e5f\u4f1a\u5bf9\u8eab\u4f53\u7684\u6b63\u5e38\u7ec6\u80de\u9020\u6210\u4e25\u91cd\u635f\u5bb3\uff0c\u5c24\u5176\u662f\u8840\u6db2\u7cfb\u7edf\u3002\u60a3\u8005\u5e38\u5e38\u4f1a\u51fa\u73b0\u8d2b\u8840\u3001\u767d\u7ec6\u80de\u51cf\u5c11\u3001\u8840\u5c0f\u677f\u51cf\u5c11\u7b49\u4e0d\u826f\u53cd\u5e94\uff0c\u8fd9\u4e0d\u4ec5\u5f71\u54cd\u4e86\u60a3\u8005\u7684\u751f\u6d3b\u8d28\u91cf\uff0c\u8fd8\u53ef\u80fd\u5bfc\u81f4\u6cbb\u7597\u4e2d\u65ad\u3002\u800c 6 – thiodg \u7684\u51fa\u73b0\uff0c\u5c31\u50cf\u662f\u5728\u9ed1\u6697\u4e2d\u70b9\u4eae\u4e86\u4e00\u76cf\u660e\u706f\uff0c\u4e3a\u764c\u75c7\u6cbb\u7597\u5e26\u6765\u4e86\u65b0\u7684\u5e0c\u671b\u3002\u5b83\u4e3a\u764c\u75c7\u6cbb\u7597\u63d0\u4f9b\u4e86\u4e00\u79cd\u5168\u65b0\u7684\u601d\u8def\uff0c\u5373\u901a\u8fc7\u9776\u5411\u764c\u7ec6\u80de\u7684\u7aef\u7c92\u673a\u5236\uff0c\u5b9e\u73b0\u5bf9\u764c\u7ec6\u80de\u7684\u7cbe\u51c6\u6253\u51fb\uff0c\u540c\u65f6\u6700\u5927\u7a0b\u5ea6\u5730\u51cf\u5c11\u5bf9\u6b63\u5e38\u7ec6\u80de\u7684\u4f24\u5bb3\u3002<\/strong><\/p>\n

\u57fa\u4e8e\u8fd9\u4e00\u53d1\u73b0\uff0c\u672a\u6765\u6709\u671b\u5f00\u53d1\u51fa\u4e00\u7cfb\u5217\u65b0\u578b\u7684\u6297\u764c\u836f\u7269\u3002\u8fd9\u4e9b\u836f\u7269\u5c06\u4ee5 6 – thiodg \u4e3a\u57fa\u7840\uff0c\u901a\u8fc7\u8fdb\u4e00\u6b65\u4f18\u5316\u548c\u6539\u8fdb\uff0c\u63d0\u9ad8\u5176\u6297\u764c\u6548\u679c\u548c\u5b89\u5168\u6027\u3002\u5b83\u4eec\u53ef\u80fd\u4f1a\u6210\u4e3a\u764c\u75c7\u6cbb\u7597\u7684\u65b0 \u201c\u5229\u5668\u201d\uff0c\u4e3a\u5e7f\u5927\u764c\u75c7\u60a3\u8005\u5e26\u6765\u798f\u97f3 \u3002\u5728\u4e34\u5e8a\u5e94\u7528\u4e2d\uff0c\u8fd9\u4e9b\u836f\u7269\u53ef\u4ee5\u5355\u72ec\u4f7f\u7528\uff0c\u4e5f\u53ef\u4ee5\u4e0e\u5176\u4ed6\u6cbb\u7597\u65b9\u6cd5\u5982\u5316\u7597\u3001\u653e\u7597\u3001\u514d\u75ab\u6cbb\u7597\u7b49\u8054\u5408\u4f7f\u7528\uff0c\u53d1\u6325\u534f\u540c\u4f5c\u7528\uff0c\u63d0\u9ad8\u764c\u75c7\u7684\u6cbb\u7597\u6548\u679c\u3002<\/strong><\/p>\n<\/section>\n

\n
<\/section>\n<\/section>\n
<\/section>\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\n
\n
\n
03\u3001<\/strong><\/em>\u4f01\u4e1a\u5408\u4f5c<\/strong><\/section>\n<\/section>\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\u501f\u52a9\u6743\u5a01\uff0c\u5f00\u62d3\u521b\u65b0<\/em><\/strong><\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
<\/section>\n
\u5bf9\u4e8e\u4f01\u4e1a\u800c\u8a00\uff0c\u4e0e Prof. Jerry W. Shay \u6559\u6388\u4ee5\u53ca\u8bfa\u5956\u5f97\u4e3bCarol W. Greider\u6559\u6388\u7b49\u7aef\u7c92\u65b9\u9762\u7684\u4e13\u5bb6\u5408\u4f5c\u80cc\u4e66\uff0c\u65e0\u7591\u662f\u4e00\u6b21\u6781\u5177\u6218\u7565\u773c\u5149\u7684\u9009\u62e9\uff0c\u5177\u6709\u8bf8\u591a\u4e0d\u53ef\u5ffd\u89c6\u7684\u4f18\u52bf\u3002\u6559\u6388\u4eec\u5728\u7aef\u7c92\u9176\u548c\u7ec6\u80de\u8870\u8001\u9886\u57df\u7684\u5d07\u9ad8\u5b66\u672f\u5730\u4f4d\u548c\u4e30\u7855\u7684\u79d1\u7814\u6210\u679c\uff0c\u5c31\u50cf\u662f\u4e00\u5757\u95ea\u95ea\u53d1\u5149\u7684\u91d1\u5b57\u62db\u724c \u3002\u4ed6\u7684\u8ba4\u53ef\u548c\u652f\u6301\uff0c\u80fd\u591f\u6781\u5927\u5730\u63d0\u5347\u4f01\u4e1a\u4ea7\u54c1\u548c\u6280\u672f\u7684\u53ef\u4fe1\u5ea6\u548c\u6743\u5a01\u6027\u3002<\/strong>\u5728\u6d88\u8d39\u8005\u8d8a\u6765\u8d8a\u6ce8\u91cd\u4ea7\u54c1\u79d1\u6280\u542b\u91cf\u548c\u7814\u53d1\u80cc\u666f\u7684\u4eca\u5929\uff0c\u6709\u4e86\u4e24\u4f4d\u6559\u6388\u7684\u80cc\u4e66\uff0c\u4f01\u4e1a\u7684\u4ea7\u54c1\u4eff\u4f5b\u88ab\u8d34\u4e0a\u4e86 \u201c\u9ad8\u54c1\u8d28\u3001\u9ad8\u79d1\u6280\u201d \u7684\u6807\u7b7e\uff0c\u66f4\u5bb9\u6613\u8d62\u5f97\u6d88\u8d39\u8005\u7684\u4fe1\u4efb\u548c\u9752\u7750\u3002\u6bd4\u5982\u5728\u6297\u8870\u8001\u62a4\u80a4\u54c1\u9886\u57df\uff0c\u82e5\u4f01\u4e1a\u7684\u4ea7\u54c1\u7814\u53d1\u5f97\u5230\u4e86\u6559\u6388\u7684\u6307\u5bfc\u6216\u8ba4\u53ef\uff0c\u6d88\u8d39\u8005\u4f1a\u66f4\u613f\u610f\u76f8\u4fe1\u8be5\u4ea7\u54c1\u5728\u5ef6\u7f13\u808c\u80a4\u8870\u8001\u65b9\u9762\u5177\u6709\u72ec\u7279\u7684\u529f\u6548\u3002<\/p>\n

\u4ea7\u5b66\u7814\u7ed3\u5408\u662f\u63a8\u52a8\u6280\u672f\u8f6c\u5316\u548c\u4ea7\u54c1\u521b\u65b0\u7684\u91cd\u8981\u9014\u5f84\u3002\u4f01\u4e1a\u62e5\u6709\u4e30\u5bcc\u7684\u5e02\u573a\u8d44\u6e90\u548c\u5f3a\u5927\u7684\u751f\u4ea7\u80fd\u529b\uff0c\u800c\u4e24\u4f4d\u6559\u6388\u5219\u638c\u63e1\u7740\u524d\u6cbf\u7684\u79d1\u7814\u6280\u672f\u548c\u521b\u65b0\u7684\u7406\u5ff5\u3002\u53cc\u65b9\u5408\u4f5c\u80fd\u591f\u5b9e\u73b0\u4f18\u52bf\u4e92\u8865\uff0c\u5c06\u79d1\u7814\u6210\u679c\u5feb\u901f\u8f6c\u5316\u4e3a\u5b9e\u9645\u4ea7\u54c1\uff0c\u63a8\u5411\u5e02\u573a\u3002<\/strong>\u5728\u5408\u4f5c\u8fc7\u7a0b\u4e2d\uff0c\u6559\u6388\u7684\u4e13\u4e1a\u77e5\u8bc6\u548c\u7814\u7a76\u6210\u679c\u53ef\u4ee5\u4e3a\u4f01\u4e1a\u7684\u4ea7\u54c1\u7814\u53d1\u63d0\u4f9b\u575a\u5b9e\u7684\u7406\u8bba\u57fa\u7840\u548c\u6280\u672f\u652f\u6301\uff0c\u5e2e\u52a9\u4f01\u4e1a\u5f00\u53d1\u51fa\u66f4\u5177\u521b\u65b0\u6027\u548c\u7ade\u4e89\u529b\u7684\u4ea7\u54c1\u3002\u4f01\u4e1a\u4e5f\u53ef\u4ee5\u4e3a\u6559\u6388\u7684\u7814\u7a76\u63d0\u4f9b\u5b9e\u8df5\u5e73\u53f0\u548c\u8d44\u91d1\u652f\u6301\uff0c\u4fc3\u8fdb\u79d1\u7814\u5de5\u4f5c\u7684\u987a\u5229\u5f00\u5c55\u3002\u8fd9\u79cd\u4e92\u5229\u5171\u8d62\u7684\u5408\u4f5c\u6a21\u5f0f\uff0c\u4e0d\u4ec5\u80fd\u591f\u63a8\u52a8\u4f01\u4e1a\u7684\u53d1\u5c55\uff0c\u4e5f\u6709\u52a9\u4e8e\u63a8\u52a8\u6574\u4e2a\u884c\u4e1a\u7684\u6280\u672f\u8fdb\u6b65\u548c\u521b\u65b0\u53d1\u5c55\u3002<\/p>\n<\/section>\n

\n
<\/section>\n<\/section>\n
<\/section>\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\u8d62\u8bfa\u8109\u5f97\uff1a\u642d\u5efa\u5408\u4f5c\u7684\u6865\u6881<\/strong><\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\u5982\u679c\u60a8\u7684\u4f01\u4e1a\u6e34\u671b\u5728\u8870\u8001\u548c\u764c\u75c7\u9886\u57df\u5b9e\u73b0\u521b\u65b0\u7a81\u7834\uff0c\u8d62\u8bfa\u8109\u5f97\u5c06\u662f\u60a8\u6700\u53ef\u9760\u7684\u5408\u4f5c\u4f19\u4f34\u3002\u4f5c\u4e3a\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u4e3a\u4f01\u4e1a\u4e0e\u9876\u5c16\u79d1\u7814\u4e13\u5bb6\u7275\u7ebf\u642d\u6865\u7684\u4e13\u4e1a\u673a\u6784\uff0c\u8d62\u8bfa\u8109\u5f97\u5728\u4fc3\u8fdb\u4ea7\u5b66\u7814\u5408\u4f5c\u65b9\u9762\u62e5\u6709\u4e30\u5bcc\u7684\u7ecf\u9a8c\u548c\u5353\u8d8a\u7684\u8d44\u6e90\u6574\u5408\u80fd\u529b \u3002\u8d62\u8bfa\u8109\u5f97\u5df2\u7ecf\u6210\u529f\u4fc3\u6210\u4e86\u4f17\u591a\u4f01\u4e1a\u4e0e\u79d1\u7814\u4e13\u5bb6\u7684\u5408\u4f5c\uff0c\u5728\u4e1a\u5185\u6811\u7acb\u4e86\u826f\u597d\u7684\u53e3\u7891 \u3002\u5176\u4e13\u4e1a\u56e2\u961f\u6df1\u5165\u4e86\u89e3\u4f01\u4e1a\u7684\u9700\u6c42\u548c\u75db\u70b9\uff0c\u80fd\u591f\u7cbe\u51c6\u5730\u4e3a\u4f01\u4e1a\u5339\u914d\u5408\u9002\u7684\u79d1\u7814\u8d44\u6e90\u3002\u5728\u4e0e Prof. Jerry W. Shay \u6559\u6388\u548c\u8bfa\u5956\u5f97\u4e3bCarol W. Greider\u6559\u6388<\/span>\u7684\u5408\u4f5c\u5bf9\u63a5\u4e2d\uff0c\u8d62\u8bfa\u8109\u5f97\u51ed\u501f\u5bf9\u6559\u6388\u7814\u7a76\u9886\u57df\u548c\u6210\u679c\u7684\u6df1\u5165\u4e86\u89e3\uff0c\u4ee5\u53ca\u4e0e\u6559\u6388\u56e2\u961f\u5efa\u7acb\u7684\u826f\u597d\u6c9f\u901a\u6e20\u9053\uff0c\u80fd\u591f\u4e3a\u4f01\u4e1a\u63d0\u4f9b\u5168\u65b9\u4f4d\u7684\u5408\u4f5c\u652f\u6301\u3002<\/strong>\u4ece\u5408\u4f5c\u610f\u5411\u7684\u521d\u6b65\u6c9f\u901a\uff0c\u5230\u5408\u4f5c\u7ec6\u8282\u7684\u534f\u5546\u6572\u5b9a\uff0c\u518d\u5230\u5408\u4f5c\u8fc7\u7a0b\u4e2d\u7684\u534f\u8c03\u4e0e\u63a8\u8fdb\uff0c\u8d62\u8bfa\u8109\u5f97\u90fd\u5c06\u5168\u7a0b\u8ddf\u8fdb\uff0c\u786e\u4fdd\u5408\u4f5c\u987a\u5229\u8fdb\u884c\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n","protected":false},"excerpt":{"rendered":"

\u7aef\u7c92\u7814\u7a76\u5f00\u521b\u8005Prof. Jerry W. Shay \u4ece\u53e4\u81f3\u4eca\uff0c\u8870\u8001\u4e00\u76f4\u662f\u4eba\u7c7b\u96be\u4ee5\u9003\u907f\u7684\u5bbf\u547d\uff0c\u4e5f\u662f\u8426\u7ed5\u5728\u5fc3\u5934\u6700…<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2946","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/www.nobelstars.cn\/index.php?rest_route=\/wp\/v2\/posts\/2946","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nobelstars.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nobelstars.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nobelstars.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nobelstars.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2946"}],"version-history":[{"count":2,"href":"https:\/\/www.nobelstars.cn\/index.php?rest_route=\/wp\/v2\/posts\/2946\/revisions"}],"predecessor-version":[{"id":2961,"href":"https:\/\/www.nobelstars.cn\/index.php?rest_route=\/wp\/v2\/posts\/2946\/revisions\/2961"}],"wp:attachment":[{"href":"https:\/\/www.nobelstars.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2946"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nobelstars.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2946"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nobelstars.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2946"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}